Structure of PDB 8ei3 Chain C Binding Site BS01

Receptor Information
>8ei3 Chain C (length=151) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPRPVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGR
RIHSYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYT
LKERCLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQERIA
H
Ligand information
>8ei3 Chain G (length=17) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DPAWWNCFSAAQQCDAM
Receptor-Ligand Complex Structure
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PDB8ei3 Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides
Resolution3.49 Å
Binding residue
(original residue number in PDB)		R60 V62 L116 T133 L135 V137 R205
Binding residue
(residue number reindexed from 1)		R3 V5 L59 T76 L78 V80 R148
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8ei3, PDBe:8ei3, PDBj:8ei3
PDBsum8ei3
PubMed37914719
UniProtP40337|VHL_HUMAN von Hippel-Lindau disease tumor suppressor (Gene Name=VHL)

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