Structure of PDB 8bwf Chain C Binding Site BS01
Receptor Information
>8bwf Chain C (length=79) Species:
9606
(Homo sapiens) [
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GPPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTE
EAANTMVNYYTSVTPVLRGQPIYIQFSNH
Ligand information
>8bwf Chain c (length=12) Species:
9606
(Homo sapiens) [
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NQKRAQKALQVN
Receptor-Ligand Complex Structure
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PDB
8bwf
Rationally designed stapled peptides allosterically inhibit PTBP1-RNA-binding.
Resolution
2.9 Å
Binding residue
(original residue number in PDB)
E72 I76 L80 K84 V85 N87 L88 K92
Binding residue
(residue number reindexed from 1)
E18 I22 L26 K30 V31 N33 L34 K38
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003676
nucleic acid binding
GO:0003723
RNA binding
View graph for
Molecular Function
External links
PDB
RCSB:8bwf
,
PDBe:8bwf
,
PDBj:8bwf
PDBsum
8bwf
PubMed
37564416
UniProt
P26599
|PTBP1_HUMAN Polypyrimidine tract-binding protein 1 (Gene Name=PTBP1)
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