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BioLiP

Structure of PDB 5vk1 Chain C Binding Site BS01

Receptor Information
>5vk1 Chain C (length=82) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDAAAQHMV
YCGGDLLGELLGRQSFSVKDPSPLYDMLRKNL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5vk1 Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design.
Resolution2.69 Å
Binding residue
(original residue number in PDB)		M53 G57 I60 M61 Q71 H72 V92
Binding residue
(residue number reindexed from 1)		M29 G33 I36 M37 Q47 H48 V68
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Cellular Component
External links
PDB RCSB:5vk1, PDBe:5vk1, PDBj:5vk1
PDBsum5vk1
PubMed30809370
UniProtO15151|MDM4_HUMAN Protein Mdm4 (Gene Name=MDM4)

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