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BioLiP

Structure of PDB 4zcf Chain C Binding Site BS01

Receptor Information
>4zcf Chain C (length=627) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TLEKNLPHQKAGVDAVMNVFVSATPHLTDNVAVRLLANPELKLSEQQYYN
NIKNVQAFNGIAHSKDNHNAKSNIIDVSMETGTGKTYTYIKTIFDLNKSF
GINKFIIIVPTLSIKAGTVNFLKSDALKEHFRDDYKRELRTYVVESQKMP
QAIHDFVEASNFKKYIHVLVINSGMINSKSLTDTYDTGLLDNQFNTPVDA
LRAVKPFIIIDEPHRFPTGKKTWENIEKFNAQYIIRYGATFSEGYKNLVY
RLTAVDAFNDDLVKGIDAYIEDNANLKFVKDGKEATFFKLAKSLSKTHSA
IHDLTLDALNTAVLSNGIELKIGSSINPYSYDQTLADNMMRKAVKEHFKL
EKELLTQPRIKPLTLFFIDDLKTKFEEYVLAEANELLYKNYLEKTVTNIS
SVHGGYIEQEINEILHDKELLLSLDNPRRFIFSKWTLREGWDNPNVFQIC
KLRSSKLQEVGRGLRLPVNEYMCRVKNFTLKYYVDFTEKDFVDSLVKEVN
ESSPSKFTQELKEQIDNFKDSDAYSRLKSELKELWDLINQKAVIEYKINS
ESEFLSIFKSFMLEETERSYREFLDNLSQTIFVKHGTLHKVFCDIKDTIL
NIQTIRKIKSGFSKYLLNNSFSLGYNL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4zcf Structural basis of asymmetric DNA methylation and ATP-triggered long-range diffusion by EcoP15I.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		N192 R230 K235 K236 T237
Binding residue
(residue number reindexed from 1)		N177 R215 K220 K221 T222
Enzymatic activity
Enzyme Commision number 3.1.21.5: type III site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0004519 endonuclease activity
GO:0005524 ATP binding
GO:0015668 type III site-specific deoxyribonuclease activity
GO:0016787 hydrolase activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:4zcf, PDBe:4zcf, PDBj:4zcf
PDBsum4zcf
PubMed26067164
UniProtQ5ZND2|T3RE_ECOLX Type III restriction-modification enzyme EcoP15I Res subunit (Gene Name=res)

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