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Structure of PDB 4xgz Chain C Binding Site BS01

Receptor Information

>4xgz Chain C (length=219) Species: 9606 (Homo sapiens)

EVQLVESGGGLVQPGGSLRLSCAASGFNVSYSSIHWVRQAPGKGLEWVAS
IYSYYGYTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARGY
YGAAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSGTAALGCLVKDYFPE
PVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNV
NHKPSNTKVDKKVEPKSCD

Ligand information

>4xgz Chain c (length=16) Species: 9606 (Homo sapiens)

NLSELDRLLLELNAVQ

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4xgz Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.
• Resolution: 2.5 Å
• Binding residue (original residue number in PDB): Y31 S33 Y52 Y53 Y54 Y56 Y58 Y96 Y97 A99
• Binding residue (residue number reindexed from 1): Y31 S33 Y52 Y54 Y55 Y57 Y59 Y100 Y101 A103

External links

• PDB: RCSB:4xgz, PDBe:4xgz, PDBj:4xgz
• PDBsum: 4xgz
• PubMed: 26087144

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