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Structure of PDB 9enc Chain B Binding Site BS01

Receptor Information
>9enc Chain B (length=285) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RAFDFSAHGRRHVALRIAYMGWGYQGFASQENTNNTIEEKLFEALTKTRL
VESRQTSNYHRCGATDKGVSAFGQVISLDLRSQFPEEIRYTHILNRVLPP
DIRILAWAPVEPSFSARFSCLERTYRYFFPRADLDIVTMDYAAQKYVGTH
DFRNLCKMNFQRTILSAQVQLVRWQEPFQLCQFEVTGQAFLYHQVRCMMA
ILFLIGQGMEKPEIIDELLNIEKNPQKPQYSMAVEFPLVLYDCKFENVKW
IYDQEAQEFNITHLQQLWANHAVKTHMLYSMLQGL
Ligand information
>9enc Chain D (length=75) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggccccaugguguaaugguuagcacucuggacuuugaauccagcgauccg
aguucaaaucucggugggaccucca
<<.<<<<..<<<<........>>>>.<<<<<.......>>>>>....<<<
<<.......>>>>>>>>>.>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9enc The molecular basis of tRNA selectivity by human pseudouridine synthase 3.
Resolution3.36 Å
Binding residue
(original residue number in PDB)		R53 R101 R166 V167 H347
Binding residue
(residue number reindexed from 1)		R1 R49 R96 V97 H263
Gene Ontology
Molecular Function
GO:0009982 pseudouridine synthase activity
GO:0016853 isomerase activity
GO:0160154 tRNA pseudouridine(38/39) synthase activity
Biological Process
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0031119 tRNA pseudouridine synthesis
GO:1990481 mRNA pseudouridine synthesis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:9enc, PDBe:9enc, PDBj:9enc
PDBsum9enc
PubMed38996458
UniProtQ9BZE2|PUS3_HUMAN tRNA pseudouridine(38/39) synthase (Gene Name=PUS3)

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