Structure of PDB 8q43 Chain B Binding Site BS01

Receptor Information
>8q43 Chain B (length=428) Species: 509193 (Thermoanaerobacter brockii subsp. finnii Ako-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNEKVLVLIVGTNPLPNYVVGSHLKEKYDKFVLIYSEKNDKINQNSTYDY
AKKLKEHLNLNDKCIFLPLSDVSNSEKIINDLREKFPSEDFVEVHLNYTG
GTKTMVVHIYNFLKEKFKFEGSYLDARDYKLVYDYSEEAISLKDTIKIDI
NTLLSIHLYEDIHFEFYDTYSYKQKFVDSFDKISQEIEKAIKDDKGEDFV
KWLEDPFRKIFKGENKLLEKTAKFKKHIEKLDSSPIVKFNEKTPQFIWDI
LNAFPEGKKLNDGQKLWIPDDKITNDNLSSRVKDTVEFLNGKWFEWYVYS
QIKSELLDRKLKEGEHFGISLKAQKKDSPYFALDIFLINGYQLIGISLTT
SSTRELCKLKGFEVIHRVRQIGGDESKAILITGMDKSKTEDLQKDLAYET
GSTQKRFVVFGIDDWADIGSKICEEVFK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8q43 Substrate selectivity and catalytic activation of the type III CRISPR-associated ancillary nuclease Can2
Resolution2.28 Å
Binding residue
(original residue number in PDB)		R213 K217 E296 N299 K301 Y339 A341 T358 T359 S360
Binding residue
(residue number reindexed from 1)		R208 K212 E287 N290 K292 Y330 A332 T349 T350 S351
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8q43, PDBe:8q43, PDBj:8q43
PDBsum8q43
PubMed38033326
UniProtE8URK0

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