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BioLiP

Structure of PDB 8pdr Chain B Binding Site BS01

Receptor Information
>8pdr Chain B (length=351) Species: 694067 (Human metapneumovirus CAN97-83) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DLSYKHAILKESQYTIKRDVGTTTAVTPSSLQQEITLLCGEILYAKHADY
KYAAEIGIQYISTALGSERVQQILRNSGSEVQVVLTRTYSLGKIKNNKGE
DLQMLDIHGVEKSWVEEIDKEARKTMATLLKESSGNIPQNQRPSAPDTPI
ILLCVGALIFTKLASTIEVGLETTVRRANRVLSDALKRYPRMDIPKIARS
FYDLFEQKVYHRSLFIEYGKALGSSSTGSKAESLFVNIFMQAYGAGQTML
RWGVIARSSNNIMLGHVSVQAELKQVTEVYDLVREMGPESGLLHLRQSPK
AGLLSLANCPNFASVVLGNASGLGIIGMYRGRVPNTELFSAAESYAKSLK
E
Ligand information
>8pdr Chain M (length=7) Species: 694067 (Human metapneumovirus CAN97-83) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DIYQLIM
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pdr Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		Y53 I103 R132 K133 M135 R151 S153
Binding residue
(residue number reindexed from 1)		Y44 I94 R123 K124 M126 R142 S144
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8pdr, PDBe:8pdr, PDBj:8pdr
PDBsum8pdr
PubMed37993464
UniProtQ6WBA1|NCAP_HMPVC Nucleoprotein (Gene Name=N)

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