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Structure of PDB 6ra9 Chain B Binding Site BS01

Receptor Information
>6ra9 Chain B (length=458) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGS
FKYAWVLDKLKAERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMI
TGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVN
KMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPATVPFVPISGWHGDNMLE
PSPNMPWFKGWKVERKEGNASGVSLLEALDTILPPTRPTDKPLRLPLQDV
YKIGGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHHEALSEAL
PGDNVGFNVKNVSVKDIRRGNVCGDSKSDPPQEAAQFTSQVIILNHPGQI
SAGYSPVIDCHTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVE
MVPGKPMCVESFSQYPPLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTK
SAQKAQKA
Ligand information
Ligand IDGPE
InChIInChI=1S/C5H14NO6P/c6-1-2-11-13(9,10)12-4-5(8)3-7/h5,7-8H,1-4,6H2,(H,9,10)/t5-/m1/s1
InChIKeyJZNWSCPGTDBMEW-RXMQYKEDSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(CO[P@](=O)(O)OC[C@@H](CO)O)N
OpenEye OEToolkits 1.5.0C(COP(=O)(O)OCC(CO)O)N
CACTVS 3.341NCCO[P](O)(=O)OC[CH](O)CO
CACTVS 3.341NCCO[P@@](O)(=O)OC[C@H](O)CO
ACDLabs 10.04O=P(OCC(O)CO)(OCCN)O
FormulaC5 H14 N O6 P
NameL-ALPHA-GLYCEROPHOSPHORYLETHANOLAMINE
ChEMBL
DrugBankDB15872
ZINCZINC000004095590
PDB chain6ra9 Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ra9 Structural Cues for Understanding eEF1A2 Moonlighting.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		A373 E374
Binding residue
(residue number reindexed from 1)		A370 E371
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ra9, PDBe:6ra9, PDBj:6ra9
PDBsum6ra9
PubMed32875694
UniProtQ71V39|EF1A2_RABIT Elongation factor 1-alpha 2 (Gene Name=EEF1A2)

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