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BioLiP

Structure of PDB 5tlv Chain B Binding Site BS01

Receptor Information
>5tlv Chain B (length=242) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQ
LLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5tlv Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution2.323 Å
Binding residue
(original residue number in PDB)		I358 K362 L372 Q375 V376 L379 E380 D538 E542
Binding residue
(residue number reindexed from 1)		I54 K58 L68 Q71 V72 L75 E76 D232 E236
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5tlv, PDBe:5tlv, PDBj:5tlv
PDBsum5tlv
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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