Structure of PDB 5f0m Chain B Binding Site BS01

Receptor Information
>5f0m Chain B (length=293) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FGPICEIDIVLNDGETRKMAEMKTEDGKVEKHYLFYDGESVSGKVNLAFK
QPGKRLEHQGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSY
DFEFMQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEYDLIVHQLATY
PDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHM
ELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDP
TPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAPE
Ligand information
Receptor-Ligand Complex Structure
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PDB5f0m Structural Mechanism for Cargo Recognition by the Retromer Complex.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		M166 E167 V168 G169 H175 R284 R285 Y286 F287
Binding residue
(residue number reindexed from 1)		M159 E160 V161 G162 H168 R277 R278 Y279 F280
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0006886 intracellular protein transport
GO:0015031 protein transport
GO:0016241 regulation of macroautophagy
GO:0032456 endocytic recycling
GO:0042147 retrograde transport, endosome to Golgi
Cellular Component
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005768 endosome
GO:0005769 early endosome
GO:0005829 cytosol
GO:0010008 endosome membrane
GO:0016020 membrane
GO:0030904 retromer complex
GO:0030906 retromer, cargo-selective complex
GO:0031982 vesicle
GO:0097422 tubular endosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5f0m, PDBe:5f0m, PDBj:5f0m
PDBsum5f0m
PubMed27889239
UniProtO75436|VP26A_HUMAN Vacuolar protein sorting-associated protein 26A (Gene Name=VPS26A)

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