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BioLiP

Structure of PDB 4bqk Chain B Binding Site BS01

Receptor Information
>4bqk Chain B (length=422) Species: 4530 (Oryza sativa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLPAMIGGVYSDDNNLQLEATTQFRKLLSIERSPPIEEVIQSGVVPRFVQ
FLTREDFPQLQFEAAWALTNIASGTSENTKVVIDHGAVPIFVKLLGSSSD
DVREQAVWALGNVAGDSPKCRDLVLANGALLPLLAQLNEHTKLSMLRNAT
WTLSNFCRGKPQPSFEQTRPALPALARLIHSNDEEVLTDACWALSYLSDG
TNDKIQAVIEAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDAQTQCI
IDHQALPCLLSLLTQNLKKSIKKEACWTISNITAGNKDQIQAVINAGIIG
PLVNLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEGCIKPLCDLLI
CPDIRIVTVCLEGLENILKVGETDKTLAAGDVNVFSQMIDEAEGLEKIEN
LQSHDNNEIYEKAVKILEAYWM
Ligand information
>4bqk Chain C (length=12) Species: 358 (Agrobacterium tumefaciens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SKRPRSERKRER
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4bqk Structural Basis of Interaction of Bipartite Nuclear Localization Signal from Agrobacterium Vird2 with Rice Importin-Alpha
Resolution1.997 Å
Binding residue
(original residue number in PDB)		F134 W138 N142 A144 S145 G146 T147 S148 T151 Q177 W180 N184 G187 D188 W223 S226 N227 R230 R306 N310 V312 G314 E346 W349 N353 A356 E388 W391 N395
Binding residue
(residue number reindexed from 1)		F62 W66 N70 A72 S73 G74 T75 S76 T79 Q105 W108 N112 G115 D116 W151 S154 N155 R158 R234 N238 V240 G242 E274 W277 N281 A284 E316 W319 N323
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0061608 nuclear import signal receptor activity
Biological Process
GO:0006606 protein import into nucleus
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4bqk, PDBe:4bqk, PDBj:4bqk
PDBsum4bqk
PubMed24503158
UniProtQ71VM4|IMA1A_ORYSJ Importin subunit alpha-1a (Gene Name=Os01g0253300)

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