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Structure of PDB 3tzx Chain B Binding Site BS01

Receptor Information
>3tzx Chain B (length=467) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELPGVTEEALRLKEAALEELAAQEVTAPLVPLAVSAFLTSRKKAAAAELA
DWMQSPEGQASSLESIGRSLSRRNHGRSRAVVLAHDHDEAIKGLRAVAAG
KQAPNVFSVDGPVTTGPVWVLAGFGAQHRKMGKSLYLRNEVFAAWIEKVD
ALVQDELGYSVLELILDDAQDYGIETTQVTIFAIQIALGELLRHHGAKPA
AVIGQSLGEAASAYFAGGLSLRDATRAICSRSHLMGEGEAMLFGEYIRLM
ALVEYSADEIREVFSDFPDLEVCVYAAPTQTVIGGPPEQVDAILARAEAE
GKFARKFATKGASHTSQMDPLLGELTAELQGIKPTSPTCGIFSTVHEGRY
IKPGGEPIHDVEYWKKGLRHSVYFTHGIRNAVDSGHTTFLELAPNPVALM
QVALTTADAGLHDAQLIPTLARKQDEVSSMVSTMAQLYVYGHDLDIRTLF
SRASGPQDYANIPPTRF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3tzx Biochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase pks13
Resolution2.3 Å
Binding residue
(original residue number in PDB)		L624 L678 P699 N700 F702 P991 P1013 Q1019 S1027
Binding residue
(residue number reindexed from 1)		L29 L83 P104 N105 F107 P396 P418 Q424 S432
Enzymatic activity
Catalytic site (original residue number in PDB) S801 L802 R826 H909 G962
Catalytic site (residue number reindexed from 1) S206 L207 R231 H314 G367
Enzyme Commision number 2.3.1.-
Gene Ontology
Molecular Function
GO:0016740 transferase activity

View graph for
Molecular Function
External links

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