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Structure of PDB 7am2 Chain Ab Binding Site BS01

Receptor Information

>7am2 Chain Ab (length=168) Species: 5689 (Leishmania tarentolae)

SRNGELCLQRIIVSYSPNKGNPAMRQFMATHLPEFHRQYPQVKIDIRPRQ
WPESSITGIYRDGSEKAYSIRFLSSMGINVRFHRLVNEGNDYNHSFSASH
LHLQRRSVQGTWNPYLWNYEGTRARHKPPAQWSRKLTEKEWDYYVQQYGA
QMKAEEDTIADRVRRYTD

Ligand information

>7am2 Chain 1 (length=797)

uuuaaucaaaguuauuauuaaauaauauugauuuuggaugaauuuaauuu
uuaauuauauuuuugaauuuuaauuuuauuauuuugauuuaauauuuuua
aaauauuauauauuuuagauuuaaauuuguuguuuuauauuuaguuuaau
guuuauaaauugauaauuaauuuguuuuauuuuaaaguuuuuaugaacug
ugauuuauaguuuauuauuuuuaguuuaauguuuaaauauuuaacuagug
auggcacaguuguucuauauguaccuauaaaaaauaguaaaauuauuuua
auuaaauuaauaaauaauuauuaaacuaauuuuauauuaauauuaugaaa
aauuuuuuuuuuuuuuaauuuuuauauauugaaguaauauggaauauuaa
aaauacaaauuuaauuuguaauuaauaaauauauuuuauuuuaauagaug
uuuaauguuaauuaauuuauuauuuuaauauuuaauauuuguuuauacaa
aaguaacuuuuuuugaauauaaagaauuauuauuauaaauauuauuuuaa
aaauauaaaaauaaauuauaacaaucuaaauaaauaauaaauuaaaauaa
aaauuuuaaaaaaaauuaaaaaauuaaaauagggcaaguccuacucuccu
uuacaaagagaacguuuauauguaauuguacuauauuuauugaaauaaua
aaaggguuggguuuuaaaaucguuguaaagcagauuuguuuauauauuua
auuuuuguauauaguuaaaaauuaauauuaguacgcaaggauucauu

....<<............<.<<............................
..........<.....>.....................>>.>........
....>>...............<<<..........>>><<<<.........
........<<....>.>..............<<....<<<<<<<.....<
<<.........................<<<........>>>.........
....>>>...<<<.....>>>.....>>>>>>>.......>>........
................<.<<<<<<............>>>>>>>.......
...........<<.............<<<<<...>>>>>.....<<<<<<
...<<<<<<<...>>>>>>>.>>>>>>...............>>......
..........................>>>>.......<............
..................................................
....<<.................>>......>...............<.<
......>.>......<<.<.<.<<.............<<..<........
..<..<<<......>>>...>.....................>....>>.
.....................>>>.>.>>...................<.
..................>............................

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7am2 Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis.
• Resolution: 3.4 Å
• Binding residue (original residue number in PDB): K20 N22 R50 Q51 W52 E54 R72 F73 F97 A99
• Binding residue (residue number reindexed from 1): K19 N21 R49 Q50 W51 E53 R71 F72 F96 A98

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0032543 mitochondrial translation

Cellular Component

• GO:0005739 mitochondrion
• GO:0005762 mitochondrial large ribosomal subunit
• GO:0005840 ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7am2, PDBe:7am2, PDBj:7am2
• PDBsum: 7am2
• PubMed: 33168716
• UniProt: Q4Q6A7

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