Structure of PDB 4v46 Chain AN Binding Site BS01

Receptor Information
>4v46 Chain AN (length=144) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VTQDCLQLIADSETPTIQKGSYTFVPWLLSFKRGSALEEKENKILVKETG
YFFIYGQVLYTDKTYAMGHLIQRKKVHVFGDELSLVTLFRCIQNMPETLP
NNSCYSAGIAKLEEGDELQLAIPRENAQISLDGDVTFFGALKLL
Ligand information
>4v46 Chain BN (length=25) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TPCVPAECFDLLVRHCVACGLLRTP
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4v46 Crystal structure of the BAFF-BAFF-R complex and its implications for receptor activation
Resolution3.3 Å
Binding residue
(original residue number in PDB)		Y206 A207 M208 G209 R231 P264 R265 E266
Binding residue
(residue number reindexed from 1)		Y65 A66 M67 G68 R90 P123 R124 E125
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005164 tumor necrosis factor receptor binding
Biological Process
GO:0006955 immune response
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v46, PDBe:4v46, PDBj:4v46
PDBsum4v46
PubMed12715002
UniProtQ9Y275|TN13B_HUMAN Tumor necrosis factor ligand superfamily member 13B (Gene Name=TNFSF13B)

[Back to BioLiP]