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BioLiP

Structure of PDB 6qzc Chain AAA Binding Site BS01

Receptor Information
>6qzc Chain AAA (length=180) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFA
SFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREP
NVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLP
FLPSTEDVYDCRVEHWGLDEPLLKHWEFDA
Ligand information
>6qzc Chain CCC (length=16) Species: 11320 (Influenza A virus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
QARQMVQAMRTIGTHP
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6qzc CD4+T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features.
Resolution1.64 Å
Binding residue
(original residue number in PDB)		Q9 E11 F24 F51 A52 S53 F54 N62 D66 N69 I72 R76
Binding residue
(residue number reindexed from 1)		Q7 E9 F22 F49 A50 S51 F52 N60 D64 N67 I70 R74
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:6qzc, PDBe:6qzc, PDBj:6qzc
PDBsum6qzc
PubMed32668259
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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