Structure of PDB 9lyz Chain A Binding Site BS01
Receptor Information
>9lyz Chain A (length=129) Species:
9031
(Gallus gallus) [
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KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGS
TDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVS
DGNGMNAWVAWRNRCKGTDVQAWIRGCRL
Ligand information
Ligand ID
AMU
InChI
InChI=1S/C11H19NO8/c1-4(10(16)17)19-9-7(12-5(2)14)11(18)20-6(3-13)8(9)15/h4,6-9,11,13,15,18H,3H2,1-2H3,(H,12,14)(H,16,17)/t4-,6-,7-,8-,9-,11-/m1/s1
InChIKey
MNLRQHMNZILYPY-YVNCZSHWSA-N
SMILES
Software
SMILES
CACTVS 3.341
C[CH](O[CH]1[CH](O)[CH](CO)O[CH](O)[CH]1NC(C)=O)C(O)=O
ACDLabs 10.04
O=C(O)C(OC1C(O)C(OC(O)C1NC(=O)C)CO)C
OpenEye OEToolkits 1.5.0
CC(C(=O)O)OC1C(C(OC(C1O)CO)O)NC(=O)C
CACTVS 3.341
C[C@@H](O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](O)[C@@H]1NC(C)=O)C(O)=O
OpenEye OEToolkits 1.5.0
C[C@H](C(=O)O)O[C@@H]1[C@H]([C@@H](O[C@@H]([C@H]1O)CO)O)NC(=O)C
Formula
C11 H19 N O8
Name
N-acetyl-beta-muramic acid;
N-acetyl-muramic acid;
BETA-N-ACETYLMURAMIC ACID
ChEMBL
DrugBank
ZINC
ZINC000004095908
PDB chain
9lyz Chain B Residue 1 [
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Receptor-Ligand Complex Structure
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PDB
9lyz
X-ray crystallography of the binding of the bacterial cell wall trisaccharide NAM-NAG-NAM to lysozyme.
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
E35 N46 D52 V109
Binding residue
(residue number reindexed from 1)
E35 N46 D52 V109
Annotation score
4
Enzymatic activity
Catalytic site (original residue number in PDB)
E35 N46 D48 S50 D52 N59
Catalytic site (residue number reindexed from 1)
E35 N46 D48 S50 D52 N59
Enzyme Commision number
3.2.1.17
: lysozyme.
Gene Ontology
Molecular Function
GO:0003796
lysozyme activity
GO:0005515
protein binding
GO:0016231
beta-N-acetylglucosaminidase activity
GO:0016798
hydrolase activity, acting on glycosyl bonds
GO:0042802
identical protein binding
Biological Process
GO:0016998
cell wall macromolecule catabolic process
GO:0031640
killing of cells of another organism
GO:0042742
defense response to bacterium
GO:0050829
defense response to Gram-negative bacterium
GO:0050830
defense response to Gram-positive bacterium
Cellular Component
GO:0005576
extracellular region
GO:0005615
extracellular space
GO:0005737
cytoplasm
GO:0005783
endoplasmic reticulum
View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:9lyz
,
PDBe:9lyz
,
PDBj:9lyz
PDBsum
9lyz
PubMed
514367
UniProt
P00698
|LYSC_CHICK Lysozyme C (Gene Name=LYZ)
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