Structure of PDB 8yrs Chain A Binding Site BS01

Receptor Information

>8yrs Chain A (length=530) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

DSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFL
VMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATML
NASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEAR
RFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHV
LTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGR
YKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWS
ANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMK
ADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQH
FDEVWNSEACNKMCDNCCKSAFERKNITEYCRDLIKILKQAEELNEKLTP
LKLIDSWMGKGAAKLRVAGVVAPTLPREDLEKIIAHFLIQQYLKEDYSFT
AYATISYLKIGPKANLLNNEAHAITMQVTK

Ligand information

>8yrs Chain P (length=13) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

agcgtcgagatcc

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8yrs Crystal structure of human RECQ1 helicase containing a flexible linker in complex with tailed duplex DNA
Resolution	2.43 Å
Binding residue (original residue number in PDB)	T521 L523 K524 Y579
Binding residue (residue number reindexed from 1)	T449 L451 K452 Y507

External links

PDB	RCSB:8yrs, PDBe:8yrs, PDBj:8yrs
PDBsum	8yrs
PubMed
UniProt	P46063\|RECQ1_HUMAN ATP-dependent DNA helicase Q1 (Gene Name=RECQL)

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