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BioLiP

Structure of PDB 8yrs Chain A Binding Site BS01

Receptor Information
>8yrs Chain A (length=530) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFL
VMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATML
NASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEAR
RFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHV
LTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGR
YKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWS
ANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMK
ADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQH
FDEVWNSEACNKMCDNCCKSAFERKNITEYCRDLIKILKQAEELNEKLTP
LKLIDSWMGKGAAKLRVAGVVAPTLPREDLEKIIAHFLIQQYLKEDYSFT
AYATISYLKIGPKANLLNNEAHAITMQVTK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8yrs Crystal structure of human RECQ1 helicase containing a flexible linker in complex with tailed duplex DNA
Resolution2.43 Å
Binding residue
(original residue number in PDB)		T521 L523 K524 Y579
Binding residue
(residue number reindexed from 1)		T449 L451 K452 Y507
External links
PDB RCSB:8yrs, PDBe:8yrs, PDBj:8yrs
PDBsum8yrs
PubMed
UniProtP46063|RECQ1_HUMAN ATP-dependent DNA helicase Q1 (Gene Name=RECQL)

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