Structure of PDB 8p4g Chain A Binding Site BS01

Receptor Information
>8p4g Chain A (length=433) Species: 178306 (Pyrobaculum aerophilum str. IM2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSAPVPPLIKEATYIEATASGYMAEGVLNPTIILRRGQRVDMTLKNKLTE
PTIVHWHGFDVNWHNDAHPSFAITPGESYNYSFDVVNRAGTYLYHPHPHG
LTAKQFYMGQLGLVIVEDSGSDLGFKYGVNDLPLVISDRRFIGGAPVYNP
TPMEMIAGFLGNAVLVNGIKDAVFKLSGGSYRLRLVNGSNARLYMLSIVK
KNGDVVPMRLIAVDQGFLARPIEVRALFLAPAERAEVVVELGEGVYLLKN
TPFDHMHLEALPEGSEYTIATFLVEGKGEAVPVEALPDPPPEPPKPTRTR
RFALSLSGMQWTINGMSWNASNPLFEHVSVEGVELWEIVNDKASMTHPVH
LHGFPMWIIERKDSPRQVAELAVDNRGRLPTDLGLKDTVLIWPGETVKIV
VNFDAKKRGQLFPFHCHNLEHEDGGMMINIAVK
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain8p4g Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8p4g Flexible active-site loops fine-tune substrate specificity of hyperthermophilic metallo-oxidases.
Resolution2.59 Å
Binding residue
(original residue number in PDB)		H391 C460 H465
Binding residue
(residue number reindexed from 1)		H347 C416 H421
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:8p4g, PDBe:8p4g, PDBj:8p4g
PDBsum8p4g
PubMed38227199
UniProtQ8ZWA8

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