Structure of PDB 8p4g Chain A Binding Site BS01

Receptor Information

>8p4g Chain A (length=433) Species: 178306 (Pyrobaculum aerophilum str. IM2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TSAPVPPLIKEATYIEATASGYMAEGVLNPTIILRRGQRVDMTLKNKLTE
PTIVHWHGFDVNWHNDAHPSFAITPGESYNYSFDVVNRAGTYLYHPHPHG
LTAKQFYMGQLGLVIVEDSGSDLGFKYGVNDLPLVISDRRFIGGAPVYNP
TPMEMIAGFLGNAVLVNGIKDAVFKLSGGSYRLRLVNGSNARLYMLSIVK
KNGDVVPMRLIAVDQGFLARPIEVRALFLAPAERAEVVVELGEGVYLLKN
TPFDHMHLEALPEGSEYTIATFLVEGKGEAVPVEALPDPPPEPPKPTRTR
RFALSLSGMQWTINGMSWNASNPLFEHVSVEGVELWEIVNDKASMTHPVH
LHGFPMWIIERKDSPRQVAELAVDNRGRLPTDLGLKDTVLIWPGETVKIV
VNFDAKKRGQLFPFHCHNLEHEDGGMMINIAVK

Ligand information

Ligand ID

InChI

InChI=1S/Cu/q+2

InChIKey

JPVYNHNXODAKFH-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Cu+2]
CACTVS 3.341	[Cu++]

Formula

Name

COPPER (II) ION

PDB chain

8p4g Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8p4g Flexible active-site loops fine-tune substrate specificity of hyperthermophilic metallo-oxidases.
Resolution	2.59 Å
Binding residue (original residue number in PDB)	H391 C460 H465
Binding residue (residue number reindexed from 1)	H347 C416 H421
Annotation score	3

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005507	copper ion binding
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding

	Cellular Component
GO:0016020	membrane

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Molecular Function

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Cellular Component

External links

PDB	RCSB:8p4g, PDBe:8p4g, PDBj:8p4g
PDBsum	8p4g
PubMed	38227199
UniProt	Q8ZWA8

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