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BioLiP

Structure of PDB 6k3k Chain A Binding Site BS01

Receptor Information
>6k3k Chain A (length=188) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQA
PHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMA
KFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHC
WDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6k3k Structural Investigations on the Interactions between Cytidine Deaminase Human APOBEC3G and DNA.
ResolutionN/A
Binding residue
(original residue number in PDB)		H216 N244 H250 F252 E254 G255 R256 H257 W285 S286 C288 Y315 D317 H367 D370 L371 R374
Binding residue
(residue number reindexed from 1)		H20 N48 H54 F56 E58 G59 R60 H61 W89 S90 C92 Y119 D121 H171 D174 L175 R178
Enzymatic activity
Enzyme Commision number 3.5.4.38: single-stranded DNA cytosine deaminase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:6k3k, PDBe:6k3k, PDBj:6k3k
PDBsum6k3k
PubMed31116511
UniProtQ9HC16|ABC3G_HUMAN DNA dC->dU-editing enzyme APOBEC-3G (Gene Name=APOBEC3G)

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