Structure of PDB 6g85 Chain A Binding Site BS01

Receptor Information
>6g85 Chain A (length=361) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RRSVYLDNTIEFLRGRVYLGAYDYTPEDTDELVFFTVEDAIFYNSFHLDF
GPMNIGHLYRFAVIFHEILNDPENANKAVVFYSSASTRQRANAACMLCCY
MILVQAWTPHQVLQPLAQVDPPFMPFRDAGYSNADFEITIQDVVYGVWRA
KEKGLIDLHSFNLESYEKYEHVEFGDFNVLTPDFIAFASPQEDHHLNQPF
KSVLNFFANNNVQLVVRLNSHLYNKKHFEDIGIQHLDLIFEDGTCPDLSI
VKNFVGAAETIIKRGGKIAVHCKAGLGRTGCLIGAHLIYTYGFTANECIG
FLRFIRPGMVVGPQQHWLYLHQNDFREWKYTTRISLKPSEAIGGLYPLIS
LEEYRLQKKKL
Ligand information
>6g85 Chain C (length=10) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
FTDVPALNYP
Receptor-Ligand Complex Structure
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PDB6g85 A PxL motif promotes timely cell cycle substrate dephosphorylation by the Cdc14 phosphatase.
Resolution1.528 Å
Binding residue
(original residue number in PDB)		H67 L70 Q106 W108 Q112
Binding residue
(residue number reindexed from 1)		H66 L69 Q105 W107 Q111
Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Gene Ontology
Biological Process
GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation

View graph for
Biological Process
External links
PDB RCSB:6g85, PDBe:6g85, PDBj:6g85
PDBsum6g85
PubMed30455435
UniProtQ00684|CDC14_YEAST Tyrosine-protein phosphatase CDC14 (Gene Name=CDC14)

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