Structure of PDB 6cnl Chain A Binding Site BS01
Receptor Information
>6cnl Chain A (length=186) Species:
9606
(Homo sapiens) [
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AKATRHIFLIRASQYHVRTLTPLGREQAELTGLRLASLGLKFNKIVHSSM
TRAIETTDIISRHLPGVCKVSTDLLREGAPIEPDPPWKPEAVQYYEDGAR
IEAAFRNYIHRADARQEEDSYEIFICHANVIRYIVCRALQFPPEGWLRLS
LNNGSITHLVIRPNGRVALRTLGDTGFMPPDKITRS
Ligand information
>6cnl Chain M (length=11) Species:
9606
(Homo sapiens) [
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GVWDPNWDRRE
Receptor-Ligand Complex Structure
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PDB
6cnl
Functional role of PGAM5 multimeric assemblies and their polymerization into filaments.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
I212 H213 R214 Q243 G268 V270
Binding residue
(residue number reindexed from 1)
I109 H110 R111 Q140 G165 V167
Enzymatic activity
Enzyme Commision number
3.1.3.16
: protein-serine/threonine phosphatase.
External links
PDB
RCSB:6cnl
,
PDBe:6cnl
,
PDBj:6cnl
PDBsum
6cnl
PubMed
30705304
UniProt
Q96HS1
|PGAM5_HUMAN Serine/threonine-protein phosphatase PGAM5, mitochondrial (Gene Name=PGAM5)
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