Structure of PDB 6c1u Chain A Binding Site BS01
Receptor Information
>6c1u Chain A (length=68) Species:
9606
(Homo sapiens) [
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GKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARY
LGNTVDLSSFDFRTGKMM
Ligand information
>6c1u Chain C (length=12) [
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cggagtgtgggc
Receptor-Ligand Complex Structure
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PDB
6c1u
Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
R166 K167 S168 L170 S171 D176 K186 R188
Binding residue
(residue number reindexed from 1)
R20 K21 S22 L24 S25 D30 K40 R42
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
View graph for
Molecular Function
External links
PDB
RCSB:6c1u
,
PDBe:6c1u
,
PDBj:6c1u
PDBsum
6c1u
PubMed
29567833
UniProt
Q9UBB5
|MBD2_HUMAN Methyl-CpG-binding domain protein 2 (Gene Name=MBD2)
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