Structure of PDB 5x54 Chain A Binding Site BS01
Receptor Information
>5x54 Chain A (length=285) Species:
9606
(Homo sapiens) [
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GRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLL
YAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGH
IYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYA
VGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGG
YDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDG
HTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
Ligand information
>5x54 Chain C (length=4) Species:
10760
(Escherichia phage T7) [
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EWWW
Receptor-Ligand Complex Structure
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PDB
5x54
Discovery of a Kelch-like ECH-associated protein 1-inhibitory tetrapeptide and its structural characterization
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
Y334 S363 R380 R415 R483 S508 G509 Q530 S555 A556 Y572 F577 S602
Binding residue
(residue number reindexed from 1)
Y10 S39 R56 R91 R159 S184 G185 Q206 S231 A232 Y248 F253 S278
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5x54
,
PDBe:5x54
,
PDBj:5x54
PDBsum
5x54
PubMed
28315327
UniProt
Q14145
|KEAP1_HUMAN Kelch-like ECH-associated protein 1 (Gene Name=KEAP1)
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