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BioLiP

Structure of PDB 5wa1 Chain A Binding Site BS01

Receptor Information
>5wa1 Chain A (length=358) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLR
RAAVGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFD
KGSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKIAA
KHYQFASGAFLHIKETVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFF
LKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKEVFPVLAAKHC
IMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYVNVKDF
SDKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQK
FTDLFEKM
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5wa1 A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability.
Resolution1.868 Å
Binding residue
(original residue number in PDB)		K147 F199 K202 M208 K209 I212 L337
Binding residue
(residue number reindexed from 1)		K147 F199 K202 M208 K209 I212 L337
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0071985 multivesicular body sorting pathway

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Biological Process
External links
PDB RCSB:5wa1, PDBe:5wa1, PDBj:5wa1
PDBsum5wa1
PubMed30181294
UniProtQ8WUM4|PDC6I_HUMAN Programmed cell death 6-interacting protein (Gene Name=PDCD6IP)

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