Structure of PDB 5vvl Chain A Binding Site BS01

Receptor Information
>5vvl Chain A (length=264) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAV
RLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKV
VRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRY
DPWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY
DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPL
IEDVLAAGEIQPPA
Ligand information
Receptor-Ligand Complex Structure
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PDB5vvl Structures of the CRISPR genome integration complex.
Resolution3.31 Å
Binding residue
(original residue number in PDB)		Y22 G23 K37 G57 R59
Binding residue
(residue number reindexed from 1)		Y7 G8 K22 G42 R44
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
GO:0005515 protein binding
GO:0008821 crossover junction DNA endonuclease activity
GO:0017108 5'-flap endonuclease activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006974 DNA damage response
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus
GO:0099048 CRISPR-cas system
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5vvl, PDBe:5vvl, PDBj:5vvl
PDBsum5vvl
PubMed28729350
UniProtQ46896|CAS1_ECOLI CRISPR-associated endonuclease Cas1 (Gene Name=ygbT)

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