Structure of PDB 5kjh Chain A Binding Site BS01

Receptor Information
>5kjh Chain A (length=481) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SAEWELPRLRTSFIFQDDYKYLQDLAEFFDVKFYPYSPPGAPPVFAATSK
KHAVICRLTQTTDKDANPCEIIQLIRDDGNEANCASCWSKDPITDQPLLC
IAGNEGNVKVYNVTEGKLYRTLVGHGGGINDLATSPANPYIIASASDDTT
IRIWSLAPEHEKQPCVCILGGEGHSYDLLSVAFHDNGRYVLSAGHDQVIN
LWALPEFPNEHMEIPIVIYYPHFSSSEIHNNLVDCVAFYGDLILSRACHE
DTIVLWRIEGFSSDDPIPGPLDAPTPTDMTKQTRSYFTPTVSPQSRPAMF
TRLAQFHTPDCGVQFFMRFRMYHVPGKHPILAFANAKSKTFFWDLARFGE
YARFMADLKEAQQSYNGRVVVVDQGISLAQAQQVHGPGVGVVMKPAWLVP
KVSASPDPDSPFGFSRETLQAWADMYDLSNPVGLIKAHRSLAIDGAFVGR
QVGWSPEGEWCVVVGNGNRALIYQRWGKERG
Ligand information
Receptor-Ligand Complex Structure
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PDB5kjh Response to Comment on "Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2".
Resolution2.27 Å
Binding residue
(original residue number in PDB)
Q35 E39 C96 N142 V325 Q326 F327 F328 R526 N542
Binding residue
(residue number reindexed from 1)
Q23 E27 C84 N130 V313 Q314 F315 F316 R450 N466
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0031491 nucleosome binding
Biological Process
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0006325 chromatin organization
Cellular Component
GO:0005634 nucleus

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5kjh, PDBe:5kjh, PDBj:5kjh
PDBsum5kjh
PubMed28008038
UniProtG0S8H7

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