Structure of PDB 5jja Chain A Binding Site BS01

Receptor Information
>5jja Chain A (length=333) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVE
YITHNRNVITEPIYPEVVHMFAVNMFRTLPPEPTLEAAWPHLQLVYEFFL
RFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGK
FLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEE
HKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKY
WPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQV
AERALYYWNNEYIMSLISDNAAKILPIMFPSLY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5jja Crystal structure of a PP2A B56-BubR1 complex and its implications for PP2A substrate recruitment and localization.
Resolution2.35 Å
Binding residue
(original residue number in PDB)		K183 H187 R197 S230 N233 G234 F235 K240 H243
Binding residue
(residue number reindexed from 1)		K141 H145 R155 S188 N191 G192 F193 K198 H201
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0019888 protein phosphatase regulator activity
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0000159 protein phosphatase type 2A complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5jja, PDBe:5jja, PDBj:5jja
PDBsum5jja
PubMed27350047
UniProtQ13362|2A5G_HUMAN Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (Gene Name=PPP2R5C)

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