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BioLiP

Structure of PDB 5dah Chain A Binding Site BS01

Receptor Information
>5dah Chain A (length=179) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRK
CESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTM
EPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTC
AQFAGLLCEEEGNGADNVQYCGYCKYHFS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5dah The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
Resolution2.611 Å
Binding residue
(original residue number in PDB)		A54 C55 L107 P110 V112 F114 V117 M120 E179 D186 N187 V188 Y190
Binding residue
(residue number reindexed from 1)		A34 C35 L87 P90 V92 F94 V97 M100 E159 D166 N167 V168 Y170
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5dah, PDBe:5dah, PDBj:5dah
PDBsum5dah
PubMed26439302
UniProtP55197|AF10_HUMAN Protein AF-10 (Gene Name=MLLT10)

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