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BioLiP

Structure of PDB 5bjt Chain A Binding Site BS01

Receptor Information
>5bjt Chain A (length=263) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWE
NQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTS
VPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTF
LLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFY
PPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIV
QHAGLAQPLRVEL
Ligand information
>5bjt Chain P (length=16) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RYFCTKWKHGWCEEVG
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5bjt Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		Y60 L122 N149 L152 T153 H161
Binding residue
(residue number reindexed from 1)		Y56 L118 N145 L148 T149 H157
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5bjt, PDBe:5bjt, PDBj:5bjt
PDBsum5bjt
PubMed28330995
UniProtP55899|FCGRN_HUMAN IgG receptor FcRn large subunit p51 (Gene Name=FCGRT)

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