Structure of PDB 4qen Chain A Binding Site BS01

Receptor Information
>4qen Chain A (length=472) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LEPHLKVTKCLRLFNKQYLLCVQAKLSRPDLKGVTEMIKAKAILYPRKII
GDLPGIDVGHRFFSRAEMCAVGFHNHWLNGIDYMSMEYEKEYSNYKLPLA
VSIVMSGQYEDDLDNADTVTYTGQGGHNLTGNKRQIKDQLLERGNLALKH
CCEYNVPVRVTRGHNCKSSYTKRVYTYDGLYKVEKFWAQKGVSGFTVYKY
RLKRLEGQPELTTDIEGLVCEDISGGLEFKGIPATNRVDDSPVSPTSGFT
YIKSLIIEPNVIIPKSSTGCNCRGSCTDSKKCACAKLNGGNFPYVDLNDG
RLIESRDVVFECGPHCGCGPKCVNRTSQKRLRFNLEVFRSAKKGWAVRSW
EYIPAGSPVCEYIGVVRRTADVNEYIFEIDCPEFCIDAGSTGNFARFINH
SCEPNLFVQCVLSSHQDIRLARVVLFAADNISPMQELTYDYGYALDSVHG
PDGKVKQLACYCGALNCRKRLY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4qen Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE.
Resolution2.002 Å
Binding residue
(original residue number in PDB)		R126 S162 R163 W175 L176 N177 G178 S204 Q206 Y207 D210 Y219 T220 Q222 G223 R241 Y273
Binding residue
(residue number reindexed from 1)		R28 S64 R65 W77 L78 N79 G80 S106 Q108 Y109 D112 Y121 T122 Q124 G125 R143 Y175
Enzymatic activity
Catalytic site (original residue number in PDB) Y475 Y593
Catalytic site (residue number reindexed from 1) Y362 Y441
Enzyme Commision number 2.1.1.-
2.1.1.367: [histone H3]-lysine(9) N-methyltransferase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0042054 histone methyltransferase activity
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Cellular Component
External links
PDB RCSB:4qen, PDBe:4qen, PDBj:4qen
PDBsum4qen
PubMed25018018
UniProtQ8GZB6|SUVH4_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4 (Gene Name=SUVH4)

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