Structure of PDB 4p6x Chain A Binding Site BS01
Receptor Information
>4p6x Chain A (length=252) Species:
9606
(Homo sapiens) [
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PQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAV
KWAKAIPGFRNLHLDDQMTLLQYSWMALMAFALGWRSYRQSSANLLYFAP
DLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKVLLLLSTI
PKDGLKSQALFDAIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSM
HEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFH
QK
Ligand information
>4p6x Chain B (length=12) Species:
9606
(Homo sapiens) [
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NALLRYLLDKDD
Receptor-Ligand Complex Structure
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PDB
4p6x
Structures and mechanism for the design of highly potent glucocorticoids.
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
V575 R585 L589 M593 L596 E755
Binding residue
(residue number reindexed from 1)
V50 R60 L64 M68 L71 E230
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4p6x
,
PDBe:4p6x
,
PDBj:4p6x
PDBsum
4p6x
PubMed
24763108
UniProt
P04150
|GCR_HUMAN Glucocorticoid receptor (Gene Name=NR3C1)
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