Structure of PDB 4nfu Chain A Binding Site BS01

Receptor Information
>4nfu Chain A (length=619) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AFEALTGINGDLITRSWSASKQAYLTERYHKEEAGAVVIFAFQPSFSEKD
FFDPDNKSSFGEIKLNRVQFPCMRKIGKGDVATVNEAFLKNLEAVIDPRT
SFQASVEMAVRSRKQIVFTGHSSGGATAILATVWYLEKYFIRNPNVYLEP
RCVTFGAPLVGDSIFSHALGREKWSRFFVNFVTRFDIVPRITLARKASVE
ETLPHVLAQLDPRNSSVQESEQRITEFYTSVMRDTSTVANQAVCELTGSA
EAILETLSSFLELSPYRPAGTFVFSTEKRLVAVNNSDAILQMLFYTCQAS
DEQEWSLIPFRSIRDHHSYEELVQSMGMKLFNHLDGENSIESSLNDLGVS
TRGRQYVQAALEEEKKRVENQKKIIQVIQQERFLKKLAWIEDEYKPKCQA
HKNGYYDSFKVSNEENDFKANVKRAELAGVFDEVLGLLKKCQLPDEFEGD
IDWIKLATRYRRLVEPLDIANYHRHLKNEDTGPYMKRGRPTRYIYAQRGY
EHHILKPNGMIAEDVFWNKVNGLNLGLQLEEIQETLKNSGSECGSCFWAE
VEELKGKPYEEVEVRVKTLEGMLREWITAGEVDEKEIFLEGSTFRKWWIT
LPKNHKSHSPLRDYMMDEI
Ligand information
Ligand IDBGC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-VFUOTHLCSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
OpenEye OEToolkits 1.7.6C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namebeta-D-glucopyranose;
beta-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL1614854
DrugBankDB02379
ZINCZINC000003833800
PDB chain4nfu Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4nfu Structural Basis for Signaling by Exclusive EDS1 Heteromeric Complexes with SAG101 or PAD4 in Plant Innate Immunity.
Resolution2.21 Å
Binding residue
(original residue number in PDB)		N285 D446
Binding residue
(residue number reindexed from 1)		N284 D445
Annotation score4
Enzymatic activity
Enzyme Commision number 3.-.-.-
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
Biological Process
GO:0006629 lipid metabolic process
GO:0006952 defense response
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4nfu, PDBe:4nfu, PDBj:4nfu
PDBsum4nfu
PubMed24331460
UniProtQ9XF23|EDS1L_ARATH Protein EDS1L (Gene Name=EDS1)

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