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BioLiP

Structure of PDB 4j9e Chain A Binding Site BS01

Receptor Information
>4j9e Chain A (length=56) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSA
YITPVN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4j9e Crystallization by capillary counter-diffusion and structure determination of the N114A mutant of the SH3 domain of Abl tyrosine kinase complexed with a high-affinity peptide ligand.
Resolution1.4 Å
Binding residue
(original residue number in PDB)		Y70 S75 D77 E98 W99 W110 P112 Y115
Binding residue
(residue number reindexed from 1)		Y6 S11 D13 E34 W35 W46 P48 Y51
Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
External links
PDB RCSB:4j9e, PDBe:4j9e, PDBj:4j9e
PDBsum4j9e
PubMed
UniProtP00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 (Gene Name=ABL1)

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