Structure of PDB 4dos Chain A Binding Site BS01

Receptor Information
>4dos Chain A (length=242) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMC
KMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVV
HGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQR
EFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKF
GQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4dos Antidiabetic phospholipid-nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		F354 R361 V371 D372 M375 E534
Binding residue
(residue number reindexed from 1)		F58 R65 V75 D76 M79 E238
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity

View graph for
Molecular Function
External links
PDB RCSB:4dos, PDBe:4dos, PDBj:4dos
PDBsum4dos
PubMed22504882
UniProtO00482|NR5A2_HUMAN Nuclear receptor subfamily 5 group A member 2 (Gene Name=NR5A2)

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