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Structure of PDB 3g8u Chain A Binding Site BS01

Receptor Information
>3g8u Chain A (length=79) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHMCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDK
IRRKNCPACRYRKCLQAGMNLEARKTKKK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3g8u DNA binding site sequence directs glucocorticoid receptor structure and activity.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		G458 S459 R466 R489 R496
Binding residue
(residue number reindexed from 1)		G22 S23 R30 R53 R60
Binding affinityPDBbind-CN: Kd=0.89uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:3g8u, PDBe:3g8u, PDBj:3g8u
PDBsum3g8u
PubMed19372434
UniProtP06536|GCR_RAT Glucocorticoid receptor (Gene Name=Nr3c1)

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