Structure of PDB 3dlh Chain A Binding Site BS01 |
| >3dlh Chain A (length=673) Species: 262724 (Thermus thermophilus HB27)
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HLGKTEVFLNRFALRPLNPEELRPWRLEVVLDPPPGREEVYPLLAQVARR
AGGVTVRMGDGLASWSPPEVLVLEGTLARMGQTYAYRLYPKGRRPLDPKD
PGERSVLSALARRLLQERLRRLEGVWVEGLAVYRREHARGPGWRVLGGAV
LDLWVSDSGAFLLEVDPAYRILCEMSLEAWLAQGHPLPKRVRNAYDRRTW
ELLRLGEEDPKELPLPGGLSLLDYHASKGRLQGREGGRVAWVADPKDPRK
PIPHLTGLLVPVLTLEDLHESLALSLPWEERRRRTREIASWIGRRLGLGT
PEAVRAQAYRLSIPKLMGRRAVSKPADALRVGFYRAQETALALLRLDGAQ
GWPEFLRRALLRAFGASGASLRLHTLHAHPSQGLAFREALRKAKEEGVQA
VLVLTPPMAWEDRNRLKALLLREGLPSQILNVPLREEERHRWENALLGLL
AKAGLQVVALSGAYPAELAVGFDAGGRESFRFGGAACAVGGGHLLWTLPE
RIPQEVVWDLLEETLWAFRRKAGRLPSRVLLLRDGRVPQDEFALALEALA
REGIAYDLVSVRKSGGGRVYPVQGRLADGLYVPLEDKTFLLLTVHRDFRG
TPRPLKLVHEAGDTPLEALAHQIFHLTRLYPASGFAFPRLPAPLHLADRL
VKEVGRLGIRHLKEVDREKLFFV |
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| PDB | 3dlh Structure of the guide-strand-containing argonaute silencing complex. |
| Resolution | 3.0 Å |
Binding residue
(original residue number in PDB) | M82 A170 Y171 R172 I173 Y197 W202 L217 Y226 H227 R232 I254 P255 H256 V264 L265 T266 L267 L279 S280 L281 R286 M413 W415 K422 I434 L435 N436 H445 R446 N449 G481 R548 R580 D609 T613 P614 R615 Y642 S645 R651 H657 R661 V685 |
Binding residue
(residue number reindexed from 1) | M80 A168 Y169 R170 I171 Y195 W200 L215 Y224 H225 R230 I252 P253 H254 V262 L263 T264 L265 L274 S275 L276 R281 M408 W410 K417 I429 L430 N431 H440 R441 N444 G476 R536 R568 D597 T601 P602 R603 Y630 S633 R639 H645 R649 V673 |
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