Structure of PDB 3c3o Chain A Binding Site BS01

Receptor Information
>3c3o Chain A (length=357) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRR
AAVGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDK
GSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKIAAK
HYQFASGAFLHIKETVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFFL
KATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKEVFPVLAAKHCI
MQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYVNVKDFS
DKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKF
TDLFEKM
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3c3o ALIX-CHMP4 interactions in the human ESCRT pathway.
Resolution2.15 Å
Binding residue
(original residue number in PDB)		D143 L146 K147 K151 F199 K202 M208 L337
Binding residue
(residue number reindexed from 1)		D142 L145 K146 K150 F198 K201 M207 L336
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0071985 multivesicular body sorting pathway

View graph for
Biological Process
External links
PDB RCSB:3c3o, PDBe:3c3o, PDBj:3c3o
PDBsum3c3o
PubMed18511562
UniProtQ8WUM4|PDC6I_HUMAN Programmed cell death 6-interacting protein (Gene Name=PDCD6IP)

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