BioLiP

Structure of PDB 1m6x Chain A Binding Site BS01

Receptor Information

>1m6x Chain A (length=399) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SQFDILCKTPPKVLVRQFVERFERPSGEKIASCAAELTYLCWMITHNGTA
IKRATFMSYNTIISNSLSFDIVNKSLQFKYKTQKATILEASLKKLIPAWE
FTIIPYNGSDITDIVSSLQLQFESGNSHSKKMLKALLSEGESIWEITEKI
LNSFEYTSRFTKTKTLYQFLFLATFINCGRFSDIKNVDPKSFKLVQNKYL
GVIIQCLVTETKTSVSRHIYFFSARGRIDPLVYLDEFLRNSEPVLKRVNR
TGNSSSNKQEYQLLKDNLVRSYNKALKKNAPYPIFAIKNGPKSHIGRHLM
TSFLSMKGLTELTNVVGNWSDKQITAIPDHYFALVSRYYAYDPISKEMIA
LKDETNPIEEWQHIEQLKGSAEGSIRYPAWNGIISQEVLDYLSSYINRR

Ligand information

>1m6x Chain E (length=13) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

taagttcctattc

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1m6x Structural Plasticity of the Flp-Holliday Junction Complex
Resolution	2.8 Å
Binding residue (original residue number in PDB)	S2 Q3 T62 S169 R170 T174 Y178 K223 N278 R281 K285 K289 N300
Binding residue (residue number reindexed from 1)	S1 Q2 T61 S158 R159 T163 Y167 K212 N267 R270 K274 K278 N289

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003690	double-stranded DNA binding
GO:0003697	single-stranded DNA binding
GO:0008301	DNA binding, bending
GO:0009009	site-specific recombinase activity

	Biological Process
GO:0006310	DNA recombination
GO:0015074	DNA integration
GO:0042150	plasmid recombination

	Cellular Component
GO:0005575	cellular_component

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PDB	RCSB:1m6x, PDBe:1m6x, PDBj:1m6x
PDBsum	1m6x
PubMed	12559911
UniProt	P03870\|FLP_YEAST Site-specific recombinase Flp (Gene Name=FLP1)