Structure of PDB 1lvm Chain A Binding Site BS01
Receptor Information
>1lvm Chain A (length=229) Species:
12227
(Tobacco etch virus) [
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GHHHHHHHGESLFKGPRDYNPISSTICHLTNESDGHTTSLYGIGFGPFII
TNKHLFRRNNGTLLVQSLHGVFKVKNTTTLQQHLIDGRDMIIIRMPKDFP
PFPQKLKFREPQREERICLVTTNFQTKSMSSMVSDTSCTFPSSDGIFWKH
WIQTKDGQCGSPLVSTRDGFIVGIHSASNFTNTNNYFTSVPKNFMELLTN
QEAQQWVSGWRLNADSVLWGGHKVFMDKP
Ligand information
>1lvm Chain C (length=6) Species:
12227
(Tobacco etch virus) [
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ENLYFQ
Receptor-Ligand Complex Structure
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PDB
1lvm
Structural basis for the substrate specificity of tobacco etch virus protease.
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
H46 D81 T146 C151 H167 S168 A169 S170 N171 F172 N174 N176 Y178 H214 K215 V216 F217 M218 K220
Binding residue
(residue number reindexed from 1)
H54 D89 T154 C159 H175 S176 A177 S178 N179 F180 N182 N184 Y186 H222 K223 V224 F225 M226 K228
Enzymatic activity
Enzyme Commision number
2.7.7.48
: RNA-directed RNA polymerase.
3.4.-.-
3.4.22.44
: nuclear-inclusion-a endopeptidase.
3.4.22.45
: helper-component proteinase.
3.6.4.-
Gene Ontology
Molecular Function
GO:0008234
cysteine-type peptidase activity
Biological Process
GO:0006508
proteolysis
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Molecular Function
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Biological Process
External links
PDB
RCSB:1lvm
,
PDBe:1lvm
,
PDBj:1lvm
PDBsum
1lvm
PubMed
12377789
UniProt
P04517
|POLG_TEV Genome polyprotein
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