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BioLiP

Structure of PDB 1hqr Chain A Binding Site BS01

Receptor Information
>1hqr Chain A (length=178) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFA
SFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREP
NVLICFIDKFTPPVVNVTWLRNGKPVTGVSETVFLPREDHLFRKFHYLPF
LPSTEDVYDCRVEHWGLDEPLLKHWEFD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1hqr Crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		Q9 W43 S53 F54 E55 N62 V65
Binding residue
(residue number reindexed from 1)		Q7 W41 S51 F52 E53 N60 V63
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:1hqr, PDBe:1hqr, PDBj:1hqr
PDBsum1hqr
PubMed11163233
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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