Structure of PDB 1hqr Chain A Binding Site BS01
Receptor Information
>1hqr Chain A (length=178) Species:
9606
(Homo sapiens) [
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EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFA
SFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREP
NVLICFIDKFTPPVVNVTWLRNGKPVTGVSETVFLPREDHLFRKFHYLPF
LPSTEDVYDCRVEHWGLDEPLLKHWEFD
Ligand information
>1hqr Chain C (length=10) Species:
9606
(Homo sapiens) [
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VHFFKNIVTP
Receptor-Ligand Complex Structure
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PDB
1hqr
Crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II.
Resolution
3.2 Å
Binding residue
(original residue number in PDB)
Q9 W43 S53 F54 E55 N62 V65
Binding residue
(residue number reindexed from 1)
Q7 W41 S51 F52 E53 N60 V63
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0006955
immune response
GO:0019882
antigen processing and presentation
Cellular Component
GO:0016020
membrane
GO:0042613
MHC class II protein complex
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:1hqr
,
PDBe:1hqr
,
PDBj:1hqr
PDBsum
1hqr
PubMed
11163233
UniProt
P01903
|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)
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