Structure of PDB 1ebp Chain A Binding Site BS01
Receptor Information
>1ebp Chain A (length=211) Species:
9606
(Homo sapiens) [
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KFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQL
EDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAASGAPRY
HRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVD
VSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFW
SAWSEPVSLLT
Ligand information
>1ebp Chain C (length=16) [
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TYSCHFGPLTWVCKPQ
Receptor-Ligand Complex Structure
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PDB
1ebp
Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A.
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
P149 M150 T151 S152 H153 F205
Binding residue
(residue number reindexed from 1)
P140 M141 T142 S143 H144 F196
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0004896
cytokine receptor activity
Cellular Component
GO:0016020
membrane
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Molecular Function
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Cellular Component
External links
PDB
RCSB:1ebp
,
PDBe:1ebp
,
PDBj:1ebp
PDBsum
1ebp
PubMed
8662530
UniProt
P19235
|EPOR_HUMAN Erythropoietin receptor (Gene Name=EPOR)
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