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BioLiP

Structure of PDB 1dc1 Chain A Binding Site BS01

Receptor Information
>1dc1 Chain A (length=310) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPFENHLKSVDDLKTTYEEYRAGFIAFALEKNKRSTPYIERARALKVAAS
VAKTPKDLLYLEDIQDALLYASGISDKAKKFLTEDDKKESINNLIENFLE
PAGEEFIDELIFRYLLFQGDSLGGTMRNIAGALAQQKLTRAIISALDIAN
IPYKWLDSRDKKYTNWMDKPEDDYELETFAKGISWTINGKHRTLMYNITV
SLVKKNVDICLFNCEPQQPEKYLLLGELKGGIDPAGADEHWKTANTALTR
IRNKFSEKGLSPKTIFIGAAIEHSMAEEIWDQLQSGSLTNSANLTKTEQV
GSLCRWIINI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1dc1 Restriction enzyme BsoBI-DNA complex: a tunnel for recognition of degenerate DNA sequences and potential histidine catalysis.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		Y74 S79 D80 K81 D124 G128 R131 N132 Y167 K185 A248 E252 K255 S287
Binding residue
(residue number reindexed from 1)		Y70 S75 D76 K77 D120 G124 R127 N128 Y163 K181 A235 E239 K242 S274
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:1dc1, PDBe:1dc1, PDBj:1dc1
PDBsum1dc1
PubMed11250198
UniProtP70985|T2B1_GEOSE Type II restriction enzyme BsoBI (Gene Name=bsoBIR)

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