Structure of PDB 1cmc Chain A Binding Site BS01

Receptor Information

>1cmc Chain A (length=104) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

AEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRH
ATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPE
TWEY

Ligand information

InChI=1S/Mg/q+2

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Mg

Name

MAGNESIUM ION

PDB chain

1cmc Chain A Residue 106 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	1cmc Three-dimensional crystal structures of Escherichia coli met repressor with and without corepressor.
Resolution	1.8 Å
Binding residue (original residue number in PDB)	H14 E19 Y104
Binding residue (residue number reindexed from 1)	H14 E19 Y104
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003700	DNA-binding transcription factor activity
GO:0005515	protein binding

	Biological Process
GO:0006355	regulation of DNA-templated transcription
GO:0006555	methionine metabolic process
GO:0009086	methionine biosynthetic process
GO:0045892	negative regulation of DNA-templated transcription

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol

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Cellular Component

External links

PDB	RCSB:1cmc, PDBe:1cmc, PDBj:1cmc
PDBsum	1cmc
PubMed	2677753
UniProt	P0A8U6\|METJ_ECOLI Met repressor (Gene Name=metJ)

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