Structure of PDB 1a1c Chain A Binding Site BS01
Receptor Information
>1a1c Chain A (length=105) Species:
9606
(Homo sapiens) [
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SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDF
DNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRL
TTVCP
Ligand information
>1a1c Chain C (length=3) [
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YEc
Receptor-Ligand Complex Structure
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PDB
1a1c
Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
R158 R178 S180 T182 H204 Y205 K206 T218 G239
Binding residue
(residue number reindexed from 1)
R14 R34 S36 T38 H60 Y61 K62 T74 G95
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
External links
PDB
RCSB:1a1c
,
PDBe:1a1c
,
PDBj:1a1c
PDBsum
1a1c
PubMed
9174343
UniProt
P12931
|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)
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