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Structure of PDB 183l Chain A Binding Site BS01

Receptor Information
>183l Chain A (length=162) Species: 10665 (Tequatrovirus T4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAI
GRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAAAI
NMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVI
TTFRTGTWDAYK
Ligand information
Ligand IDDEN
InChIInChI=1S/C9H8/c1-2-5-9-7-3-6-8(9)4-1/h1-6H,7H2
InChIKeyYBYIRNPNPLQARY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341C1C=Cc2ccccc12
OpenEye OEToolkits 1.5.0c1ccc2c(c1)CC=C2
ACDLabs 10.04c1cccc2c1C=CC2
FormulaC9 H8
NameINDENE
ChEMBLCHEMBL192812
DrugBank
ZINCZINC000001699888
PDB chain183l Chain A Residue 400 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB183l Specificity of ligand binding in a buried nonpolar cavity of T4 lysozyme: linkage of dynamics and structural plasticity.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		V87 Y88 A99 L118
Binding residue
(residue number reindexed from 1)		V87 Y88 A99 L118
Annotation score1
Binding affinityMOAD: Ka=5170M^-1
Enzymatic activity
Catalytic site (original residue number in PDB) E11 D20
Catalytic site (residue number reindexed from 1) E11 D20
Enzyme Commision number 3.2.1.17: lysozyme.
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0009253 peptidoglycan catabolic process
GO:0016998 cell wall macromolecule catabolic process
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium
GO:0044659 viral release from host cell by cytolysis
Cellular Component
GO:0030430 host cell cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:183l, PDBe:183l, PDBj:183l
PDBsum183l
PubMed7612599
UniProtP00720|ENLYS_BPT4 Endolysin (Gene Name=E)

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