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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1935574
Molecular formula	C16H17N5O
IUPAC name	7-(furan-2-yl)-4-piperazin-1-ylquinazolin-2-amine
Molecular weight	295.346
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	1.7
Synonyms	BDBM50361012 SCHEMBL3363811
Inchi Key	UBEJREHBDACTGD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H17N5O/c17-16-19-13-10-11(14-2-1-9-22-14)3-4-12(13)15(20-16)21-7-5-18-6-8-21/h1-4,9-10,18H,5-8H2,(H2,17,19,20)
PubChem CID	56835171
ChEMBL	CHEMBL1935574
IUPHAR	N/A
BindingDB	50361012
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
332466	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
332467	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
332468	Histamine H1 receptor	P70174	Hrh1	Mus musculus (Mouse)	488
332469	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
332472	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445
332473	Histamine H3 receptor	P58406	Hrh3	Mus musculus (Mouse)	445
332465	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390
332470	Histamine H4 receptor	Q91ZY2	Hrh4	Mus musculus (Mouse)	391
332471	Histamine H4 receptor	Q91ZY1	Hrh4	Rattus norvegicus (Rat)	391

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