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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	1,3-Dipropylxanthine
Molecular formula	C11H16N4O2
IUPAC name	1,3-dipropyl-7H-purine-2,6-dione
Molecular weight	236.275
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	1.9
Synonyms	1,3-Dipropyl-3,7-dihydro-purine-2,6-dione BDBM50227331 D0R3DN NSC_169317 UNII-Z02T66W92D 1,3-dipropyl-xanthine AC1Q6LGS FT-0667703 PDSP1_001233 1,3-Dipropyl-1H-purine-2,6(3H,7H)-dione 1H-Purine-2,6-dione, 3,9-dihydro-1,3-dipropyl- ANW-66126 Cystic fibrosis therapy (CPX), SciClone L000861 PDSP2_001217 1,3-Dipropyl-3,9-dihydro-purine-2,6-dione BDBM82032 DB-068477 PDSP1_000328 Z02T66W92D AJ-51820 CHEMBL157655 GTPL427 PDSP2_000326 1,3-dipropyl-3,7-dihydro-1h-purine-2,6-dione 31542-62-8 AX8236472 D03KKK MJVIGUCNSRXAFO-UHFFFAOYSA-N SCHEMBL515771 1,3-dipropyl-7H-purine-2,6-dione AC1L53IX CAS_169317 DTXSID00185447 PDSP1_000983 ZINC4654890 1,3-di-n-propylxanthine 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dipropyl- AKOS016004647 CTK4G7324 J-018455 PDSP2_000967 [ Show all ]
Inchi Key	MJVIGUCNSRXAFO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H16N4O2/c1-3-5-14-9-8(12-7-13-9)10(16)15(6-4-2)11(14)17/h7H,3-6H2,1-2H3,(H,12,13)
PubChem CID	169317
ChEMBL	CHEMBL157655
IUPHAR	427
BindingDB	82032
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
207209	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
207211	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
207212	Adenosine receptor A1	P47745	ADORA1	Cavia porcellus (Guinea pig)	326
207213	Adenosine receptor A1	P49892	ADORA1	Gallus gallus (Chicken)	324
207210	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
207215	Adenosine receptor A2a	P46616	ADORA2A	Cavia porcellus (Guinea pig)	409
207216	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410
207214	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332
207217	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318

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