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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Niguldipine(+)
Molecular formula	C36H39N3O6
IUPAC name	5-O-[3-(4,4-diphenylpiperidin-1-yl)propyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-3,4-dihydropyridine-3,5-dicarboxylate
Molecular weight	609.723
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	6.2
Synonyms	BDBM82424 NSC_1236 CAS_1236
Inchi Key	MFGFAKSTFYWAKE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C36H39N3O6/c1-25-31(34(40)44-3)33(27-12-10-17-30(24-27)39(42)43)32(26(2)37-25)35(41)45-23-11-20-38-21-18-36(19-22-38,28-13-6-4-7-14-28)29-15-8-5-9-16-29/h4-10,12-17,24,31,33H,11,18-23H2,1-3H3
PubChem CID	54069298
ChEMBL	N/A
IUPHAR	N/A
BindingDB	82424
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
204025	Alpha-1A adrenergic receptor	Q9WU25	ADRA1A	Cavia porcellus (Guinea pig)	466
204027	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
556292	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
204026	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
204028	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572

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