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Name | Alpha-1A adrenergic receptor |
---|---|
Species | Cavia porcellus (Guinea pig) |
Gene | ADRA1A |
Synonym | Alpha-1A adrenoceptor Alpha-1A adrenoreceptor Alpha-1C adrenergic receptor |
Disease | N/A for non-human GPCRs |
Length | 466 |
Amino acid sequence | MVFLSGNASDSSNCTQPPAPVNIPKAILLGVILGVLILFGVPGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMSLCIISIDRYIGVSYPLRYPTIVTQRRGLRALLCLWALSLVISIGPLFGWRQPAPQDETICQINEDPSYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLTSGLKTDKSDSEQVTLRIHRKNAPLGGSGVASSKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLKIQCLRRKQSSKHALGYTLHPPSQAVEGQHKDMVRIPVGSRETFYKISKTDGVCEWKFFSSMPRGSARITVPKDQSACTTARVRSKSFLQVCCCVGPSTPNPGENHQVPTIKIHTISLSENGEEV |
UniProt | Q9WU25 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL2150843 |
IUPHAR | N/A |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
17884 | Bmy-7378 | C22H31N3O3 | 385.508 | 5 / 0 | 2.8 | Yes |
61767 | CID 10621591 | C20H26ClNO6 | 411.879 | 7 / 1 | N/A | N/A |
62241 | spiperone | C23H26FN3O2 | 395.478 | 5 / 1 | 3.0 | Yes |
105678 | CID 10834792 | C19H23ClFNO5 | 399.843 | 7 / 1 | N/A | N/A |
115732 | 5-Methylurapidil | C21H31N5O3 | 401.511 | 6 / 1 | 1.9 | Yes |
131031 | CHEMBL2153551 | C19H24ClNO6 | 397.852 | 7 / 3 | N/A | N/A |
131352 | prazosin | C19H21N5O4 | 383.408 | 8 / 1 | 2.0 | Yes |
164327 | CHEMBL215421 | C19H24ClNO5 | 381.853 | 6 / 2 | N/A | N/A |
171796 | thioridazine | C21H26N2S2 | 370.573 | 4 / 0 | 5.9 | No |
204025 | Niguldipine(+) | C36H39N3O6 | 609.723 | 8 / 0 | 6.2 | No |
291490 | risperidone | C23H27FN4O2 | 410.493 | 6 / 0 | 2.7 | Yes |
299031 | methiothepin | C20H24N2S2 | 356.546 | 4 / 0 | 4.2 | Yes |
312978 | dl-Arterenol | C8H11NO3 | 169.18 | 4 / 4 | -1.2 | Yes |
321783 | CHEMBL2153555 | C19H23Cl2NO5 | 416.295 | 6 / 2 | N/A | N/A |
324188 | CID 10549595 | C20H26ClNO6 | 411.879 | 7 / 1 | N/A | N/A |
333741 | AC1NJ58P | C9H13NO3 | 183.207 | 3 / 3 | -0.7 | Yes |
346457 | SCHEMBL8097715 | C25H27NO5 | 421.493 | 6 / 1 | 4.4 | Yes |
375892 | Skf 104856 | C14H14ClNS | 263.783 | 2 / 0 | 4.2 | Yes |
385776 | oxymetazoline | C16H24N2O | 260.381 | 2 / 2 | 2.9 | Yes |
434097 | chlorpromazine | C17H19ClN2S | 318.863 | 3 / 0 | 5.2 | No |
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